Consumption coagulopathy in neonates born to mothers with pregnancy induced hypertension.

Pregnancy induces complex changes concerned with hemostasis. Normal pregnancy is associated with hypercoagulable state which becomes more pronounced at term while in pre-eclampsia or pregnancyinduced hypertension (PIH), localized coagulation fibrinolytic imbalance has been reported(l,2). Various coagulation factors are decreased in concentration in PIH, especially fibrinogen, factor V, VII, VIII. Thrombocytopenia and increased serum FDP levels are alto observed(3). In term and preterm neonates of these mothers, a variety of coagulation alterations with significant thrombocytopenia have been reported(4,5).